Figure 2.
Cost-effectiveness analysis of erlotinib versus placebo, via the cost-effectiveness plane. Panel (a) shows the distribution of (Δe,Δc) under the assumption of zero completely at random and for both the Gamma/Beta (in blue) and the log-Normal/Beta (in red) models. Panel (b) shows the same quantities under the assumption of zero at random. In either case, the contour plots are extremely similar, indicating very limited sensitivity to the zero mechanisms as well as to the distributional assumptions for the cost distribution.