Table I. Response to Two Courses of Induction Chemotherapy, According to the Survivin-2B/ΔEx2 Ratio.
Survivin-2B/ΔEx2 <1 (n = 68) | Survivin-2B/ΔEx2 ≥ 1(n = 22) | ||||
---|---|---|---|---|---|
|
|
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N | % | N | % | P-value | |
Phase 1 (course 1) response | |||||
CR | 59 | 88 | 10 | 45 | <0.001 |
PR | 3 | 4 | 3 | 14 | 0.158 |
Fail | 2 | 3 | 5 | 23 | 0.009 |
Death | 3 | 4 | 4 | 18 | 0.060 |
Not evaluable | 1 | 0 | |||
Phase 2 (course 2) cumulative response | |||||
CR | 47 | 80 | 12 | 57 | 0.044 |
PR | 3 | 5 | 0 | 0 | 0.563 |
Fail | 3 | 5 | 5 | 24 | 0.026 |
Death | 6 | 10 | 4 | 19 | 0.442 |
Not evaluable | 9 | 1 |
CR, complete remission; PR, partial remission.