Table II. Outcome for All Patients According to the Survivin-2B/ΔEx2 Ratio.
Survivin-2B/ΔEx2 <1 (n = 68) | Survivin-2B/ΔEx2 ≥ 1 (n = 22) | ||||
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N | % ± 2SE% | N | % ± 2SE% | P-value | |
5-year OS from study entry | 68 | 60 ± 12 | 22 | 36 ± 21 | 0.011 |
5-year EFS from study entry | 68 | 53 ± 12 | 22 | 23 ± 18 | 0.001 |
5-year OS from end of course 1 | 59 | 65 ± 13 | 10 | 60 ± 31 | 0.665 |
5-year DFS from end of course 1 | 59 | 57 ± 13 | 10 | 40 ± 31 | 0.323 |
5-year RR from end of course 1 | 59 | 31 ± 12 | 10 | 60 ± 31 | 0.061 |
5-year TRM from end of course 1 | 59 | 12 ± 9 | 10 | 0 ± 0 | 0.263 |
5-year OS from end of course 2 | 47 | 70 ± 14 | 12 | 50 ± 29 | 0.134 |
5-year DFS from end of course 2 | 47 | 61 ± 14 | 12 | 33 ± 27 | 0.066 |
5-year RR from end of course 2 | 47 | 32 ± 14 | 12 | 58 ± 28 | 0.056 |
5-year TRM from end of course 2 | 47 | 6 ±7 | 12 | 8 ± 16 | 0.834 |
OS, overall survival; EFS, event-free survival; DFS, disease-free survival; RR, relapse rate; TRM, treatment-related mortality; SE, standard error.