. Author manuscript; available in PMC: 2015 Jan 6.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2014 Jul 15;89(4):804–813. doi: 10.1016/j.ijrobp.2014.03.041

Table 1.

Agreement in contours for the total GTV of each case^*

Parameter	HCC1 GTV	HCC2 GTV	HCC3 GTV
No. of experts	11	10	11
Volume maximum (cm³)	83.71	116.38	211.63
Volume minimum (cm³)	54.55	87.94	88.78
Volume average (cm³)	66.47	101.61	157.86
Volume SD (cm³)	±9.93	±9.79	±43.12
Volume intersection	45.21	52.74	51.22
Volume union	100.34	164.70	311.03
STAPLE volume	66.27	121.23	210.01
Kappa agreement	0.826 Near perfect	0.804 Substantial	0.711 Substantial

Abbreviations: GTV = gross tumor volume; HCC1, -2, -3 = hepatocellular carcinoma case 1, 2, 3; STAPLE = simultaneous truth and performance level estimation.

Total GTV is the primary gross tumor volume (GTV) plus tumor venous thrombus (TVT).