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. Author manuscript; available in PMC: 2015 Jan 6.
Published in final edited form as: Gastroenterology. 2007 May 21;133(2):647–658. doi: 10.1053/j.gastro.2007.05.022

Figure 6.

Figure 6

PTEN is a target for miR-21. HCC cells were plated in 6-well plates. Cells were transfected with 1 μg of a Renilla luciferase expression construct pRL-TK and 1 μg of the pGL3-PTEN-3′-UTR firefly luciferase expression construct, along with either anti–miR-21 or control inhibitor. An increase in relative firefly luciferase activity in the presence of anti-miR-21 indicates that the 3′-UTR of PTEN contains a target that is modulated by miR-21. Data represent mean ± standard error from 8 separate determinations. *P < .05 when compared with controls.