Table 2.
Highly Expressed miRNA in Human HCC Cell Lines
| SK-HEP-1
|
SNU-182
|
SNU-449
|
PLC/PRF-5
|
Hep-G2
|
|||||
|---|---|---|---|---|---|---|---|---|---|
| miRNA | Mean ± SE | miRNA | Mean ± SE | miRNA | Mean ± SE | miRNA | Mean ± SE | miRNA | Mean ± SE |
| miR-21 | 10.0 ± .2 | let-7i | 8.1 ± 1.1 | miR-21 | 8.6 ± .6 | miR-20 | 12.56 ± 1.2 | miR-192 | 8.5 ± 1.6 |
| miR-221 | 6.7 ± .6 | miR-221 | 8.1 ± 1.1 | let-7f-2 | 6.6 ± .8 | miR-122a | 10.45 ± 2.1 | miR-34a | 6.8 ± .3 |
| let-7i | 5.8 ± .6 | miR-222 | 6.1 ± .6 | let-7a-1 | 5.7 ± .8 | miR-192 | 6.8 ± 1.3 | miR-20 | 6.3 ± .5 |
| miR-222 | 4.6 ± .3 | miR-29b | 5.0 ± .3 | let-7f-1 | 5.3 ± .5 | miR-21 | 6.1 ± .3 | miR-106a | 5.8 ± .8 |
| let-7a-1 | 4.5 ± 1.1 | miR-21 | 4.7 ± .1 | let-7c | 4.6 ± .6 | miR-106a | 5.8 ± 1.1 | miR-92-1 | 5.0 ± .3 |
| let-7c | 3.9 ± 1.0 | miR-181b1 | 4.7 ± .6 | miR-23a | 4.6 ± .2 | miR-221 | 5.5 ± .8 | miR-17-5p | 4.7 ± .6 |
| miR-125b-1 | 3.8 ± .3 | miR-20 | 4.6 ± .5 | let-7d | 4.1 ± .5 | miR-194-1 | 5.3 ± 1.0 | miR-194-1 | 4.0 ± .8 |
| let-7f-2 | 3.4 ± .7 | miR-92-1 | 4.3 ± .3 | miR-221 | 3.9 ± .4 | miR-17-5p | 4.9 ± .8 | miR-148a | 3.9 ± .7 |
| miR-34a | 2.6 ± .1 | miR-106a | 4.0 ± .6 | miR-16-1 | 3.8 ± .2 | miR-23a | 4.6 ± .3 | miR-30b | 3.8 ± .3 |
| let-7f-1 | 2.6 ± .5 | miR-34a | 3.6 ± .2 | miR-23b | 3.8 ± .3 | miR-16-1 | 3.8 ± .5 | miR-26a-1 | 3.3 ± .2 |
| miR-29b | 2.5 ± .1 | miR-16-1 | 3.4 ± .2 | miR-29b | 3.7 ± .2 | miR-15a | 3.7 ± .7 | miR-93 | 3.3 ± .3 |
| miR-23a | 2.4 ± .1 | let-7a-1 | 3.4 ± .2 | miR-181b1 | 3.5 ± .4 | miR-222 | 3.6 ± .3 | miR-25 | 2.7 ± .1 |
| miR-92-1 | 2.4 ± .3 | let-7c | 3.1 ± .4 | miR-222 | 3.2 ± .3 | miR-26a-1 | 3.6 ± .3 | miR-29b | 2.6 ± .3 |
| let-7d | 2.4 ± .7 | miR-23a | 3.1 ± .2 | miR-30a-5p | 3.0 ± .3 | miR-92-1 | 3.3 ± .1 | miR-146 | 2.6 ± .4 |
| miR-20 | 2.3 ± .2 | miR-138-1 | 2.8 ± .4 | miR-27a | 2.9 ± .2 | miR-23b | 3.2 ± .3 | miR-186 | 2.5 ± .1 |
| miR-16-1 | 2.3 ± .2 | miR-17-5p | 2.8 ± .4 | miR-24-1 | 2.8 ± .1 | miR-27a | 3.1 ± .1 | miR-126* | 2.3 ± .2 |
| miR-106a | 2.0 ± .1 | miR-100 | 2.8 ± .4 | miR-93 | 2.8 ± .3 | miR-93 | 3.1 ± .4 | miR-200b | 2.2 ± .3 |
| miR-27a | 1.7 ± .1 | miR-27a | 2.8 ± .1 | miR-25 | 2.6 ± .2 | miR-29b | 2.8 ± .2 | miR-340 | 2.1 ± .1 |
| miR-138-1 | 1.7 ± .1 | let-7d | 2.7 ± .4 | let-7i | 2.6 ± .3 | miR-22 | 2.7 ± .2 | miR-103-1 | 2.1 ± .3 |
| miR-26a-1 | 1.6 ± .1 | miR-196a-1 | 2.8 ± .3 | miR-98 | 2.5 ± .2 | miR-197 | 2.6 ± .3 | miR-128a | 2.0 ± .2 |
NOTE. Expression data are normalized to that in normal human hepatocytes.