Table 1.
Nonlaboratory measures
| Test | Baseline | Month 1 | Month 3 | Month 6 | Month 8 |
|---|---|---|---|---|---|
| Off treatment | Treatment | Treatment | Off treatment | ||
| Intake | + | + | − | + | |
| Cognition | |||||
| Grooved pegboard | + | + | − | + | + |
| Elithorn maze | − | + | − | − | + |
| Digit symbol | + | + | − | + | + |
| Digit vigilance | + | + | − | + | + |
| Hopkins verbal | − | + | − | − | + |
| Stroop | + | + | − | + | + |
| Digit span | + | − | − | + | − |
| Trail making | + | + | − | + | + |
| ANART | − | − | − | + | − |
| Behavior | |||||
| PSAP | † | † | − | † | † |
| Conflict tactics | + | + | − | + | + |
| OAS-M | + | + | − | + | + |
| Life history of aggression | + | − | − | − | − |
| SSQ-Conflict | + | − | + | + | |
| Proxy interview, irritability | − | − | + | − | − |
| Barratt impulsiveness | − | † | − | − | † |
| Cardiovascular | |||||
| Blood pressure, heart rate | − | + | − | + | + |
| Cardiovascular reactivity | † | − | − | † | − |
| Mood | |||||
| CES-D | + | + | − | + | + |
| Hospital anxiety | − | † | − | − | † |
| Wakefield | † | † | − | † | † |
| Proxy interview, mood | − | − | + | − | − |
| Quality of life (QOL) | |||||
| SF-12v2 | + | + | − | + | + |
| Symptom survey | + | + | + | + | + |
| Sleep visual analog | + | + | − | + | + |
| Overall QOL | − | ||||
| Other | |||||
| Statin study questionnaire (some questions distributed across visits, e.g., family history) | + | + | − | + | + |
| Dropouts for cause | |||||
| Compliance | |||||
| Medication adherence counseling | + | − | + | − | − |
| Compliance | |||||
| MEMSCAP | − | + | + | + | + |
| Consent, reconsent | + | − | + | − | − |
| Pill count | − | † | † | † | † |
| Compliance query | − | † | † | † | † |
| SSQ conscientiousness |
+: Test done;
−: Test not done;
†
: Test performed in a subset.