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(a) Age at onset of symptoms in the total cohort (n = 1914), among female patients (n = 985) and among male patients (n = 929). (b) Age at diagnosis in the total cohort (n = 2134), among female patients (n = 1094) and among male patients (n = 1040). An age of 0 years means less than 12 months of age (reproduced from 1, copyright 2014, with permission from Elsevier).
