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. 2014 Oct 17;29(1):216–226. doi: 10.1096/fj.14-261693

Figure 1.

Figure 1.

11-REs localize to the RPE in zebrafish larvae. A) Representative HPLC chromatogram at 325 nm of lipophilic extracts of 5 dpf zebrafish larvae. B) Spectral characteristics of extracted retinoids from zebrafish larvae. C) In vivo 2-photon microscopy images of different layers of the zebrafish larval eye. Retinosomes were exclusively detected in the RPE (far-right image). 1, 11-REs; 2, at-REs; 3, syn 11-RAL oxime (syn 11-RAL); 3′, anti 11-RAL oxime (anti 11-RAL); 4, syn all-trans-retinal (all-RAL); Abs., absorbance; AU, absorbance units.