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Acylcarnitine treatment does not affect C2C12 myotube cytokine secretion at concentrations that elicit insulin resistance. A) IL-6 secretion of C2C12 myotubes. B) IL-6, (C) iMCP1, (D) PTGS-2, (E) TNF-α gene expression in C2C12 myotubes. A–E) See Materials and Methods for details concerning myotube treatments. ***P < 0.001, treated cells vs. basal. Data are shown as mean ± sem.
