TABLE 1.
Characteristics of human muscle biopsy donors
| Control (n = 5) | Obese, insulin-resistant (n = 5) | |
|---|---|---|
| Sex | Female | Female |
| Age (y) | 44.4 ± 7.2 | 45.0 ± 9.1 |
| BMI (kg/m2) | 19.9 ± 1.4 | 35.9 ± 2.3* |
| % fat | 23.1 ± 7.5 | 47.1 ± 1.8* |
| Resting metabolic rate (kJ) | 5255 ± 286 | 7207 ± 385* |
| Fasting blood glucose (mmol/L) | 4.8 ± 0.5 | 5.1 ± 0.3 |
| Fasting plasma insulin (pmol/L) | 19.0 ± 7.8 | 62.4 ± 13.4* |
| HOMA-IR | 0.6 ± 0.02 | 2.1 ± 0.52* |
| HbA1C (%) | 5.2 ± 0.4 | 5.3 ± 0.2 |
BMI, body mass index; HOMA-IR, homeostatic model assessment–insulin resistance; HbA1C, hemoglobin A1C.
*
P < 0.001, obese, insulin resistant vs. control.