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Fifty percent neutralization concentration (EC50) (µM) against clade B HIV-1
| Assay | HIV-1MN(CXCR4-tropic) | HIV-1BaL(CCR5-tropic) |
|---|---|---|
| Maraviroc | >0.1 | 0.002 ± 0.001 |
| KD-247 Fab | 0.2 ± 0.06 | 0.1 ± 0.02 |
| KD-247 scFv | 0.7 ± 0.2 | 0.6 ± 0.1 |
| N27dD scFv | 2.1 ± 0.7 | 1.2 ± 0.2 |
| Y92F scFv | 0.8 ± 0.08 | 0.5 ± 0.09 |
Data represent the mean ± sd from the results of three independent experiments.
