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. 2014 Oct 23;29(1):105–115. doi: 10.1096/fj.14-256503

Figure 1.

Figure 1.

Effect of macrophage (MØ) depletion on wound healing and neutrophil infiltration. A) Representative images of fluorescein-stained corneas at days 2 and 4 after injury in control and MØ-depleted HO-2+/+ (WT) and HO-2−/− mice. B) Wound closure as percent change from day 0. Results are mean ± sem; n = 10–20. *P < 0.05 and **P < 0.01 from control WT mice. C) Neutrophil infiltration into the cornea at day 4 after injury. Left, WT mice; right, HO-2−/− mice; white bars, control mice receiving PBS liposomes; black bars, MØ-depleted mice receiving clodronate liposomes. Results are mean ± sem; n = 6–10. *P < 0.05 and **P < 0.01 from control (PBS liposome-treated) WT mice.