Table 1. Patient characteristics in Oxford Plaque Study and Athero-Express.
| Characteristic | Oxford Plaque (n=481) | Athero-Express (n=1159) | P value | ≤ 30-days (n=553) | >30-days (n=1087) | P value |
|---|---|---|---|---|---|---|
| Median 1year stroke risk [IQ range] | 7.6 [5.1-12.0] | 8.3 [5.4-11.8] | 0.360 | 11.0 [8.2-15.2] | 6.77 [5.0-9.9] | <0.001 |
| Median 5 year stroke risk [IQ range] | 19.0 [12.2-29.4] | 21.0 [14.0-29.0] | 0.014 | 27.22 [20.8-36.1] | 17.3 [11.7-24.8] | <0.001 |
| Age, years (±SD) | 67.0 (±8.7) | 69.0 (±9.4) | <0.001 | 68.6 (±9.6) | 68.3 (±9.0) | 0.42 |
| Male gender | 71.9% (346/481) | 65.9% (762/1158) | 0.017 | 65.6 (363/553) | 68.7 (746/1086) | 0.21 |
| Median time since last event, days [IQ range] | 87 [34-150] | 45 [18-95] | <0.001 | NA | NA | |
| Presenting event | ||||||
| Monocular | 27.0% (130/481) | 16.7% (193/1159) | <0.001 | 17.7 (98/553) | 20.7 (225/1087) | 0.15 |
| TIA , single | 10.8% (52/481) | 36.8% (426/1159) | <0.001 | 26.6 (147/553) | 30.5 (331/1087) | 0.10 |
| TIA, multiple | 28.9% (139/481) | 15.4% (179/1159) | <0.001 | 28.8 (159/553) | 14.6 (159/1087) | <0.001 |
| Minor stroke | 7.3% (35/481) | 17.6% (203/1159) | <0.001 | 13.4 (74/553) | 15.1(164/1087) | 0.35 |
| Major stroke | 26.0% (125/481) | 13.5% (157/1159) | <0.001 | 13.6 (75/553) | 19.1 (208/1087) | 0.005 |
| Diabetes | 10.8% (52/481) | 17.9% (207/1159) | <0.001 | 17.9 (99/553) | 14.7 (160/1087) | 0.10 |
| Treated hypertension | 58.2% (280/481) | 59.2% (680/1149) | 0.717 | 56.5 (310/549) | 60.1 (650/1081) | 0.16 |
| Treated hypercholesterolaemia* | 17.9% (86/481) | 74.5% (828/1111) | <0.001 | 62.9 (329/523) | 54.7 (584/1068) | 0.002 |
| Previous myocardial infarction | 12.1% (58/481) | 9.6% (108/1121) | 0.145 | 12.2 (65/531) | 9.4 (101/1070) | 0.08 |
| Peripheral vascular disease | 17.5% (84/481) | 17.2% (194/1128) | 0.898 | 19.7 (105/534) | 16.1 (173/1074) | 0.08 |
Abbreviations: IQ, Interquartile; SD, Standard deviation; TIA, Transient ischemic attack.
*
As measured by prior statin use