Table 3. Odds-ratios for the presence of non-overlapping individual plaque characteristics in the highest versus lowest quartile of stroke risk.
Plaque characteristic | Oxford Plaque Study (n=481) | Athero-Express (n=1159) | ||||
---|---|---|---|---|---|---|
OR | 95% CI | P-value | OR | 95% CI | P-value | |
1 YEAR STROKE RISK | ||||||
Plaque rupture | 1.33 | 0.81-2.20 | 0.26 | NA | NA | NA |
Foam cells | 0.82 | 0.49-1.36 | 0.43 | NA | NA | NA |
Plaque lymphocytes | 1.18 | 0.71-1.95 | 0.53 | NA | NA | NA |
Thin Cap | 1.28 | 0.73-2.24 | 0.39 | NA | NA | NA |
Cap inflammation | 0.82 | 0.44-1.52 | 0.52 | NA | NA | NA |
Smooth muscle cells | NA | NA | NA | 0.70 | 0.48-1.02 | 0.06 |
5 YEAR STROKE RISK | ||||||
Plaque rupture | 1.39 | 0.85-2.27 | 0.19 | NA | NA | NA |
Foam cells | 0.81 | 0.49-1.33 | 0.40 | NA | NA | NA |
Plaque lymphocytes | 1.21 | 0.74-1.99 | 0.44 | NA | NA | NA |
Thin Cap | 1.17 | 0.68-2.02 | 0.57 | NA | NA | NA |
Cap inflammation | 0.95 | 0.52-1.73 | 0.87 | NA | NA | NA |
Smooth muscle cells | NA | NA | NA | 0.72 | 0.50-1.05 | 0.09 |
Abbreviation: NA, not available.