Table 3. Comparisons of Clinical Variables at Initial Assessment Between Patients With RCBPI and RCBP1I and a Recent History of Substance Use Disorder.
| Variable | RCD PI (N = 191) | RCBI (N = 54) | RCBPI vs RCBPII | |||
|---|---|---|---|---|---|---|
|
|
|
|
||||
| Mean | SD | Mean | SD | Wald 95% CI | P | |
| Addiction Severity Index composite scores | ||||||
| Medical | 0.25 | 0.32 | 0.19 | 0.3 | −0.03 to 0.15 | .2044 |
| Employment | 0.46 | 0.29 | 0.41 | 0.27 | −0.03 to 0.13 | .2418 |
| Alcohol | 0.27 | 0.24 | 0.31 | 0.23 | −0.11 to 0.13 | .2677 |
| Drug | 0.09 | 0.1 | 0.09 | 0.09 | −0.03 to 0.03 | 1.0000 |
| Legal | 0.1 | 0.18 | 0.12 | 0.21 | −0.08 to 0.04 | .5272 |
| Family/social support | 0.32 | 0.25 | 0.27 | 0.21 | −0.02 to 0.12 | .1415 |
| Psychiatric | 0.59 | 0.14 | 0.51 | 0.15 | 0.04 to 0.13 | .0007* |
| Total | 0.3 | 0.1 | 0.28 | 0.09 | −0.01 to 0.05 | .1614 |
| Episodes in past 12 mo, no. | ||||||
| Mania/hypomania | 6.8 | 4.86 | 6.35 | 4.26 | −0.88 to 1.78 | .5075 |
| Depression | 6.91 | 5.72 | 6.41 | 4.27 | −0.90 to 1.90 | .4855 |
| Total | 13.71 | 10.12 | 12.76 | 8.51 | −1.74 to 3.64 | .4884 |
| Global Assessment Scale scores | 51.15 | 7.46 | 53.57 | 7.53 | −4.69 to -0.15 | .0405 |
*
Still significant after Bonferroni adjustment (.05/45); the adjusted p value = .0011.
Abbreviations: RCBPI = rapid-cycling bipolar I disorder, RCBPII = rapid-cycling bipolar II disorder.