Serum antibody reactivity to a recombinant serpin, representing spot
1a (GI: 224589270), and a recombinant purinin representing spot 2a
(BU_purinin #3). (A) SDS-PAGE profile of the purified recombinant
serpin (lane 1) and purinin (lane 2) proteins, following Coomassie
staining. (B–E) Immunoblotting with the recombinant proteins,
demonstrating IgA (B,D) and IgG (C,E) antibody reactivity to serpin
(B,C) and purinin (D,E). Lanes 1 and 2 correspond to sera from two
representative patients, while lanes 3 and 4 represent sera from two
healthy controls. Molecular weight markers are shown to the left of
each panel (in kDa).