Fig. 3.
The CAS-CPT conjugated nanoparticle constructs show excellent stability and photo-triggered release. (a) Scheme for conjugation of CAS-CPT on silica NPs. (b) Release of CPT monitored over time after 10 mins of UV light exposure (365 nm, 2.5 mW/cm2) using fluorescence spectroscopy. (c) Release of CPT measured after varying times of UV light exposure (0 – 20 mins). Measurements were acquired 24 hrs after UV exposure, using absorption spectroscopy (top) and fluorescence spectroscopy (bottom, λex = 368 nm). (d) Absorbance spectra measured over 21 days in the absence of UV exposure (black & red), followed by 10-min UV irradiation after 21 days (blue).