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. Author manuscript; available in PMC: 2015 Oct 3.
Published in final edited form as: J Mater Chem B. 2014 Oct 3;2(44):7685–7693. doi: 10.1039/C4TB01436G

Fig. 5.

Fig. 5

Cancer cells exhibit dose-dependent sensitivity to the CPT drug photo-released from hydrogel-NP hybrid scaffolds. (a) Cell culture setup for assessing CPT drug delivery to U87 glioblastoma brain cancer cells. (b) Images of hydrogel-NP hybrid scaffolds generated in cell culture inserts. (c) Phase images of brain cancer cells after four days in varying conditions: control (untreated cells), hydrogel without NPs, hydrogel-NP without UV irradiation and hydrogel-NP with 10-min UV irradiation (365 nm, 2.5 mW/cm2). Scale bars = 50 μm. (d) Cellular viability after four days in the presence of varying NP-loaded hydrogels (n = 3), with and without UV irradiation (normalized to control untreated cells).