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. 2013 Dec 6;232(1):87–97. doi: 10.1002/path.4286

Figure 2.

Figure 2

Characteristics of PVAT in diabetic and HFD-fed obese mice. (A) H&E-stained sections of PVAT surrounding the abdominal aorta of control (C57BL/6), ob/+ and ob/ob mice. (B) Time course changes of PVAT morphology in mice fed HFD for 5, 10 and 15 weeks. Representative images are from five or six independent experiments: Ao, abdominal aorta. Bottom in each group: (A) immunohistochemical staining for macrophages (CD68+) in PVAT of control (C57BL/6), ob/+ and ob/ob mice. (B) Time course of macrophage infiltration in PVAT of HFD-fed mice. Representative images are from five or six independent experiments: *area where adipocytes are enlarged; arrows, macrophage staining.