Comparison of Background Characteristics in Preterm Infants
| EP (n = 52) | PTC (n = 41) | Δ (95% CI), EP–PTC | |
|---|---|---|---|
| Boys (%) | 25 (48%) | 26 (63%) | −15% (−34%; 5%) |
| Gestational age (weeks) | 25.6 (1.0) | 34.7 (1.3) | −9.1 (−9.6; −8.6)*** |
| Birth weight (kg) | 0.80 (0.1) | 2.21 (0.5) | −1.4 (−1.6; −1.2)*** |
| Birth weight z-score1 | −0.3 (0.7) | −0.4 (1.1) | 0.1 (−0.3; 0.5) |
| Birthweight <10th percentile1 (%) | 4/52 (8%) | 10/41 (24%) | −17% (−32%; −2%)* |
| Maternal smoking, antenatally | 5 (10%) | 3 (7%) | 2% (−11%; 14%) |
| Maternal smoking, postnatally | 5 (10%) | 10 (24%) | −15% (−31%; 0%) |
| Maternal antenatal steroids | 43 (90%)2 | 20 (50%)3 | 40% (21%; 56%)** |
| PROM >24 hr | 20 (51%)4 | 12 (31%)4 | 21% (−1%; 40%) |
| Prior respiratory morbidity | |||
| (a) Bronchodilator ever | 19/42 (45%) | 5/38 (13%) | 32% (12%; 49%)** |
| (b) LRI post discharge | 12/42 (29%) | 2/38 (5%) | 23% (7%; 39%)** |
Data presented as n (%) or mean (SD).
EP, extremely preterm; PTC, preterm control; PROM, prolonged rupture of membranes; LRI, lower respiratory illness.
Δ mean difference between groups.
1
Calculated using the UK-WHO algorithm.15
2
n = 48.
3
n = 40.
4
n = 39.
*
P ≤ 0.05.
**
P ≤ 0.01.
***
P ≤ 0.001.