Table 2.

Prenatal microarray studies focused on abnormal ultrasound (AUS) only

	Sample sizea	Platform	No. pCNC	pCNC %
AUS only studies
Tyreman et al.5	106	Affymetrix Gene Chip 6.0	11	10.4
D'Amours et al.6	49	BAC/105 and 135k oligo	6	12.2
Evangelidou et al.7	15	1 Mb BAC	2	13.3
Valduga et al.8	50	44k oligo	5	10.0
Faas et al.9	30	250k SNP	2	6.7
Srebniak et al.10	199	105k SNP	16	8.0
Le Caignec et al.11	49	BAC targeted	3	6.1
Rooryck et al.12	142	60k oligo	16	11.3
Subtotal	640		61	9.5
Other studies
Wapner et al.14	755	Targeted with 1 Mb backbone	45	6.0
Shaffer et al.15	2081	Various	131	6.3
Lee et al.16	180	BAC targeted/60k oligo	20	11.1
Fiorentino et al.17	74	BAC targeted	5	6.8
Subtotal	3090		201	6.5
Combined studies	3730		262	7.0

^aNormal conventional karyotypes only.