Table 1.
Demographics of the study population and clinical symptoms
| Characteristics | All patients (n = 105) | Moderate/severe illness (n = 15) |
|---|---|---|
| Age, mean and range | 50 (40–63) | 58 (43–73) |
| Gender, female/male (n) | 56/49 | 8/7 |
| Hospital care | 72% | 100% |
| Days of hospital care (mean and range) | 4 (0–55) | 12 (1–55) |
| Fever | 98% | 100% |
| Headache | 74% | 47% |
| Backache | 51% | 33% |
| Nausea/vomiting | 51% | 53% |
| Respiratory symptoms | 41% | 67% |
| Lower respiratory symptoms | 26% | 53% |
| Abdominal pains | 35% | 40% |
| Blurred vision | 21% | 33% |
| Renal impairment (creatinine > normal range) | 88% | 87% |
| Renal impairment (creatinine >4 times normal) | 33% | 60% |
| Haemorrhagic manifestations | 28% | 33% |
| Thrombocytopenia (<100 × 109/L) | 71% | 93% |
| Thrombocytopenia (<50 × 109/L) | 34% | 80% |
Respiratory symptoms included all symptoms from both the upper and lower respiratory tract. Lower respiratory tract symptoms were defined as dyspnoea, hypoxia and obstructivity. Creatinine levels reported in (μM) were used as a marker for renal impairment, when described as over normal range or more than four times normal for women and men, respectively.