Table 2.
Laboratory findings in association with disease severity
| All patients (n = 105) | Mild illness (n = 90) | Moderate/severe illness (n = 15) | p-value | Normal range | |
|---|---|---|---|---|---|
| Max. CRP (mg/L) | 68 (11–254) | 65 (11–236) | 82 (29–254) | 0.083 | <3 mg/L |
| Min. platelets (109/L) | 72 (12–397) | 79 (19–397) | 35 (12–182) | <0.001 | Females 165–387, Males 145–348 |
| Max. WBC (109/L) | 9.5 (4–50) | 9.2 (4–22) | 14.3 (8–50) | <0.001 | 3.5–8.8 |
| Max. neutrophils (109/L) | 5.8 (2.8–18.3) | 5.6 (2.8–13.1) | 7.2 (5.3–18.3) | <0.001 | 1.8–6.3 |
| Max. lymphocytes (109/L) | 2.1 (0.6–6.2) | 2.1 (0.6–6.2) | 2.6 (0.6–6.0) | 0.927 | 1.0–3.5 |
| Max. monocytes (109/L) | 0.9 (0.4–3.2) | 0.9 (0.4–2.4) | 1.1 (0.4–3.2) | 0.352 | 0.3–1.2 |
| Max. creatinine (μM) | 232 (60–1634) | 222 (60–1548) | 370 (136–1634) | 0.01 | Females 45–90, Males 60–105 |
| Min. sodium (mM) | 136 (107–146) | 136 (121–146) | 130 (113–144) | 0.064 | 137–145 |
| Max. potassium (mM) | 4.4 (3.3–6.3) | 4.5 (3.3–6.3) | 4.4 (3.8–5.0) | 0.346 | 3.6–4.6 |
| Max. ALT (μkat/L) | 1.2 (0.33–7.81) | 1.2 (0.3–7.8) | 1.2 (0.3–3.6) | 0.797 | Females <0.75, Males <1.1 |
| Max. AST (μkat/L) | 1.0 (0.35–4.45) | 1.0 (0.35–4.5) | 1.2 (0.6–3.5) | 0.209 | Females <0.6, Males <0.75 |
| Max. LD (μkat/L) | 5.6 (2.6–11.8) | 5.4 (2.6–11.8) | 7.0 (4.2–10.3) | 0.008 | <4.2 |
| IgG titre | 1:320 (neg–1:5120) | 1:320 (neg–1:5120) | 1:40 (neg–1:1280) | 0.023 |
CRP, C-reactive protein; WBC, white blood cell count; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LD, lactate dehydrogenase.
Laboratory values were given as medians, range within parentheses. The p-value was calculated using Mann–Whitney U test.
The median IgG titre is presented as median and range. Negative samples represent titres <1 : 40.