Table 1.
N | All (N = 2077) | Men (N = 1010) | Women (N = 1067) | p Value gender difference | |
---|---|---|---|---|---|
Novel coronary heart disease risk factors (age 60–64) – geometric mean (SD) | |||||
C-Reactive protein (mg/l) | 2063 | 2.31 (2.43) | 2.24 (2.46) | 2.39 (2.41) | 0.087 |
Interleukin-6 (pg/ml) | 2049 | 2.08 (2.03) | 2.15 (2.02) | 2.01 (2.05) | 0.033 |
E-selectin (ng/ml) | 2049 | 35.35 (1.57) | 36.81 (1.56) | 34.02 (1.57) | <0.001 |
Tissue-plasminogen activator (ng/ml) | 1795 | 8.51 (1.85) | 9.09 (1.84) | 7.98 (1.85) | <0.001 |
Proinsulin (pmol/l) | 1795 | 8.82 (2.03) | 10.06 (2.08) | 7.78 (1.93) | <0.001 |
Leptin (ng/ml) | 2053 | 12.56 (2.56) | 7.53 (2.16) | 20.35 (2.29) | <0.001 |
Adiponectin (μg/ml) | 2051 | 11.77 (2.06) | 8.55 (2.00) | 15.91 (1.85) | <0.001 |
Socioeconomic positiona– N (%) | |||||
Childhood (age 4) | |||||
I and II | 1975 | 508 (25.7) | 247 (25.5) | 261 (25.9) | 0.93 |
IIInm | 396 (20.0) | 189 (19.5) | 207 (20.5) | ||
IIIm | 571 (28.9) | 283 (29.2) | 288 (28.6) | ||
IV and V | 500 (25.3) | 248 (25.6) | 252 (25.0) | ||
Early adulthood (age 26) | |||||
I and II | 1981 | 689 (34.8) | 392 (40.7) | 297 (29.1) | <0.001 |
IIInm | 624 (31.5) | 145 (15.1) | 479 (47.0) | ||
IIIm | 391 (19.7) | 304 (31.6) | 87 (8.5) | ||
IV and V | 277 (14.0) | 121 (12.6) | 156 (15.3) | ||
Middle age (age 53) | |||||
I and II | 2000 | 962 (48.1) | 556 (56.6) | 406 (39.9) | <0.001 |
IIInm | 467 (23.4) | 103 (10.5) | 364 (35.8) | ||
IIIm | 306 (15.3) | 234 (23.8) | 72 (7.1) | ||
IV and V | 265 (13.3) | 90 (9.2) | 175 (17.2) | ||
Body mass index –mean (SE) | |||||
Age 4 (kg/m2) | 1799 | 16.18 (1.64) | 16.31 (1.67) | 16.06 (1.61) | 0.0014 |
Age 26 (kg/m2) | 1821 | 22.67 (2.91) | 23.19 (2.73) | 22.19 (2.99) | 0.0000 |
Age 53 (kg/m2) | 1965 | 27.13 (4.51) | 27.24 (3.75) | 27.02 (5.11) | 0.2959 |
Age 60–64 (kg/m2) | 2071 | 27.86 (4.88) | 27.91 (4.10) | 27.80 (5.51) | 0.6153 |
Cigarette smoking | |||||
Pack years to age 53– mean (SE) | 1660 | 9.99 (0.33) | 11.54 (0.50) | 8.49 (0.42) | 0.0000 |
At age 60–64 – N (%) | |||||
Never smoked | 1889 | 911 (48.2) | 385 (42.0) | 526 (54.1) | <0.001 |
Ex-smoker | 773 (40.9) | 434 (47.4) | 339 (34.8) | ||
Light current smoker | 72 (3.8) | 31 (3.4) | 41 (4.2) | ||
Moderate current smoker | 99 (5.2) | 42 (4.6) | 57 (5.9) | ||
Heavy current smoker | 34 (1.8) | 24 (2.6) | 10 (1.0) |
Socioeconomic position: I and II = professional and intermediate; IIInm = skilled non-manual; IIIm = skilled manual; IV and V = partly skilled or unskilled.