Table 3.
Variants of histone H2B in humans
| Variants | Name of genes | Genomic location (Ensembl) | Protein length (aa) (Swiss-Prot) | Function (references) |
|---|---|---|---|---|
| H2B type 1-A | HIST1H2BA | 6p22.2 | 127 | Specific role of H2B variants is poorly understood. It is probable that they specialize in chromatin compaction and transcription repression, particularly during gametogenesis (Kamakaka and Biggins 2005) |
| H2B type 1-B | HIST1H2BB | 6p22.2 | 126 | |
| H2B type 1-c/E/F/G/I | HIST1H2BG | 6p22.2 | 126 | |
| HIST1H2BF | ||||
| HIST1H2BE | ||||
| HIST1H2BI | ||||
| HIST1H2BC | ||||
| H2B type 1-D | HIST1H2BD | 6p22.2 | 126 | |
| H2B type 1-H | HIST1H2BH | 6p22.2 | 126 | |
| H2B type 1-J | HIST1H2BJ | 6p22.1 | 126 | |
| H2B type 1-K | HIST1H2BK | 6p22.1 | 126 | |
| H2B type 1-L | HIST1H2BK | 6p22.1 | 126 | |
| H2B type 1-M | HIST1H2BM | 6p22.1 | 126 | |
| H2B type 1-N | HIST1H2BN | 6p22.1 | 126 | |
| H2B type 1-O | HIST1H2BN | 6p22.1 | 126 | |
| H2B type 2-E | HIST2H2BE | 1q21.2 | 126 | |
| H2B type 2-F | HIST2H2BF | 1q21.2 | 126 | |
| H2B type 3-B | HIST3H2BB | 1q42.13 | 126 | |
| H2B type F-M | H2BFM | Xq22.2 | 257 | |
| H2B type F-S | H2BFS | 21q22.3 | 126 | |
| H2B type W-T | H2BFWT | Xq22.2 | 175 | |
| putative H2B type 2-C | HIST2H2BC | 1q21.2 | 193 | |
| putative H2B type 2-D | HIST2H2BD | 1q21.2 | 164 |