Table 2. Differentially Expressed Proteins in Human Colostral Whey between Women with and without Gestational Diabetes Mellitus.

protein	accessiona	non-GDMb	GDMb	FDc	Padjd	ranke
Higher in GDM
apolipoprotein D	P05090	17.1 ± 12	48.1 ± 20	2.8	0.002	8
Ig heavy chain V–II region ARH-77	P06331	1.15 ± 1.7	2.04 ± 1.6	1.8	0.015	2
prostasin	Q16651	4.59 ± 2	7.95 ± 4.2	1.7	0.041	5
Lower in GDM
alpha-2-HS-glycoprotein	P02765	20.1 ± 8.6	9.36 ± 4.4	0.5	0.048	7
apolipoprotein A1	P02647	38.2 ± 13	16.8 ± 14	0.4	0.012	1
apolipoprotein E	P02649	9.81 ± 5.3	3.21 ± 3	0.3	0.017	6
14–3–3 protein zeta/delta	P63104	6.23 ± 3.3	2.11 ± 1.8	0.3	0.028	10
protein disulfide-isomerase	P07237	1.36 ± 1.7	0.275 ± 0.51	0.2	0.050	9
protein DJ-1	Q99497	1.08 ± 0.79	0.097 ± 0.24	0.1	0.007	3
protein FAM3B	P58499	2.77 ± 1.6	0.876 ± 1.3	0.3	0.032	4

^aUniprot database identifier (http://www.uniprot.org/).

^bValues are reported as the mean ± standard deviation of normalized total spectra.

^cFold difference, FD; of the means of normalized total spectra for GDM relative to non-GDM.

^dFalse discovery rate adjusted (q = 0.05) P-value for power law global error model.

^eRankings are based on the absolute values of the O-PLS-DA model loadings on the LV1 for shown proteins.