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. Author manuscript; available in PMC: 2015 Jan 7.
Published in final edited form as: Nutr Cancer. 2012;64(7):1058–1069. doi: 10.1080/01635581.2012.716898

FIG. 1.

FIG. 1

Effect of RQC on apoptosis of MDA-MB-231 cells. Apoptosis of MDA-MB-231 cells was detected by caspase 3 activity assays following 48 and 96 h incubation with vehicle (Veh) or combined resveratrol (Res), quercetin (Quer), and catechin (Cat) at 5 μM each (RQC). A: Caspase 3 activity relative to Veh (n=3 ± SEM) as quantified from absorbance at 405 nm of p-nitroaniline, a product released by caspase 3 activity. An asterisk indicates statistical significance (p≤0.05) when compared to vehicle. B: Apoptotic signaling proteins regulated in MDA-MB-231 cells at 48 h following Veh or 5 μM RQC treatment were studied using antibody arrays. Normalized data was analyzed using average integrated density signal for the two replicates of each antibody. A representative image of 3 biological replicates is presented. Proteins that were significantly regulated by RQC are highlighted.