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. Author manuscript; available in PMC: 2015 Jan 7.
Published in final edited form as: Mol Imaging Biol. 2009 Dec 1;12(3):286–294. doi: 10.1007/s11307-009-0273-5

TABLE 4.

Input Function Estimation Error for UCLA Mice FDG Datasets. (mean ± standard deviation)(%).

# Blood Samples CWRU HSIDO
AUC 0 34.3 ± 52.4 −2.9 ± 28.6
1 6.0 ± 21.2 * 2.5 ± 11.5 *
2 −5.3 ± 13.3 −0.8 ± 12.3

CWRU: Input function estimation method in Ref. 3.

HSIDO: Input function estimation method developed in this study.

*

Measurement precision improves significantly (P<0.05) over the same measurement obtained with one less blood sample.

HSIDO based measurement has significantly smaller bias (P<0.05) than CWRU based measurement.

HSIDO based measurement has significantly better precision (P<0.05) than CWRU based measurement.