Figure 2.
High temperature growth and auxotrophic analysis. Wild type (KN99α), ura4::NeoR (FGC003), reconstituted strain ura4Δ+URA4 (FGC003R1), ura5 mutant and the original insertional mutant G368 were incubated on the following media at 30°C and 37°C for 48 hours: YPD; YNB supplemented with 2% glucose, 5 g/L ammonium sulfate, and amino acids (YNB), with or without addition of uracil (20μM) or uridine (20μM); and 5-FOA (5-fluoroorotic acid) medium (10 mg/mL). From left to right the amount of cells inoculated in each spot is: 1 × 104, 1 × 103, 1 × 102, 1 × 101 and 1 cell.