Table 1. Selected cell repository test cell lines.
| Name (CCLV RIE reference number) | Species | Age | Tissue | Split ratio | PrPC | Inocula # |
|---|---|---|---|---|---|---|
| KM-2-R (89) | cattle | fetus | spleen | 1:2 | + | BSE |
| KZ-R (93) | cattle | fetus | tongue | 1:2 | + | BSE |
| KNN-R (96) | cattle | fetus | adrenal gland | 1:2 | + | BSE |
| KMU-R (98) | cattle | neonate | muscle | 1:2 | - | |
| PES (154) | cattle | adult | kidney, BVDV+ | 1:2 | + | BSE, scrapie, RML |
| KHY (239) | cattle | neonate | pituitary gland | 1:2 | + | BSE, RML, ME7 |
| KOP-R (244) | cattle | neonate | oesopharynx | 1:2 | + | BSE |
| MDBK (84) | cattle | adult | kidney, BVDV+ | 1:6 | + | BSE, scrapie |
| MDBK (261) | cattle | adult | kidney | 1:6 | + | BSE, scrapie |
| GGE-R (456) | cattle | embryo | brain | 1:2 | + | BSE, RML, ME7 |
| GRE-R (458) | cattle | embryo | brain | 1:2 | + | BSE, scrapie, RML, ME7 |
| FKD-1-R (970) | cattle | fetus | gut | 1:2 | + | BSE |
| FP-R (972) | cattle | fetus | rumen | 1:2 | + | BSE |
| FRD-R (979) | cattle | fetus | gut | 1:2 | + | BSE |
| PT (11) | sheep | adult | kidney | 1:6 | - | BSE, scrapie |
| PO (17) | sheep | adult | kidney | 1:6 | - | |
| SFN-R (39) | sheep | neonate | kidney | 1:2 | + | scrapie |
| SFH-R (42) | sheep | neonate | testis | 1:2 | - | |
| SFT-R (43) | sheep | neonate | thymus | 1:3 | - | |
| SPLW-R (150) | sheep | lamb | plexus chorioideus | 1:6 | - | |
| SLU-L (151) | sheep | adult | pulmonary tumor | 1:6 | + | scrapie |
| OFC (157) | sheep | fetus | cornea | 1:2 | - | |
| SE-R (174) | sheep | embryo | embryo | 1:2 | - | |
| ESP (201) | sheep | embryo | plexus chorioideus | 1:2 | + | BSE, scrapie, RML, ME7 |
| SCP (213) | sheep | embryo | plexus chorioideus | 1:2 | + | BSE, scrapie, RML, ME7 |
| SP-R (279) | sheep | adult | plexus chorioideus | 1:2 | - | |
| ZLU-R (120) | goat | fetus | lung | 1:2 | + | BSE, scrapie, caprine scrapie |
| ZLI-R (130) | goat | fetus | labium | 1:2 | + | BSE, scrapie, caprine scrapie |
| ENG-R (242) | mink | embryo | brain | 1:2 | + | BSE, ME7, RML |
| KG-R (252) | cat | neonate | brain | 1:2 | + | BSE, ME7, RML |
| WSG-R (378) | wild pig | fetus | brain | 1:4 | + | BSE |
| CBS (266) | domestic pig | fetus | cerebellum | 1:4 | + | BSE |
| SGW-R (565) | domestic pig | weaned | brain stem | 1:4 | + | BSE, ME7, RML |
| DWM-R (766) | fallow deer | embryo | stomach | 1:2 | - | BSE |
| REH-R (822) | roe deer | fetus | testis | 1:2 | - | BSE |
| REN-R (821) | roe deer | fetus | kidney | 1:2 | - | |
| RPS-R (824) | roe | fetus | mucosa of rumen | 1:2 | - | |
| HEK-293 (197) | human | embryo | kidney | 1:4 | + | BSE |
| Oligo (221) | human | embryo | oligodendroglia | 1:4 | + | |
| K562 (439) | human | unknown | myeloid leukemia | 1:4 | + | |
| U373 (675) | human | adult | astrocytoma | 1:2 | + | BSE |
| L,NCTC/L-929 (14) | mouse | adult | connective tissue | 1:6 | + | BSE, RML |
| N2a (132) | mouse | adult | neuroblastoma | 1:3,1:10 | + | RML |
| N2a (229) | mouse | adult | neuroblastoma | 1:3 | + | BSE, scrapie, RML |
| M0/0 (864) | mousePrP0/0 | neonate | brain | 1:2,1:10 | - | BSE |
| MGbov (900) | mousePrP0/0PrPbov | embryo | brain | 1:3 | + | BSE, scrapie, RML, murine BSE |
| MGOV-R 23a (969) | mousePrP0/0PrPov | embryo | brain | 1:4 | + | BSE, scrapie, RML |
| MGOV-R 28 (969) | mousePrP0/0PrPov | embryo | brain | 1:3 | + | scrapie, RML |
| CHO-K1 (134) | hamster | adult | ovary | 1:6 | + | BSE, RML |
| RK-13 (109) | rabbit | adult | epithelial cells | 1:4 | - | |
| RLI-R (750) | rabbit | adult | liver, immortalized | 1:6 | - | |
| JKM (795) | rabbit | young | spleen | 1:2 | - | |
| T34 (830) | rabbit | adult | spleen | 1:2 | - | |
| KMK-R (901) | rabbit | adult | bone marrow | 1:2 | - |
# bold: successful infection; italic: transient infection, but not repeatable (data not shown)