Table 1.
Oncogenic viral gene products triggering the production of mitochondrial reactive oxygen species.
| Virus | Viral protein | Mechanism to induce mROS production | Reference |
|---|---|---|---|
| HBV | HBX | May alter the expression of proteins involved in oxidative phosphorylation. | Jung & Kim, 2013, Koike, 2009, Lee et al., 2004 |
| HCV | Core | Inhibits oxidative phosphorylation complex I. | Korenaga et al., 2005 |
| Stimulates calcium uniporter activity. | Li et al, 2007 | ||
| HPV | E2 | Unknown | |
| HTLV-1 | p13 | Induces an inward potassium current at the mitochondrial inner membrane. |
Silic-Benussi et al., 2009 Biasiotto et al., 2010 |
| Tax | Unknown |