TABLE 3.
Sensitivities for Computer-Aided Detection (CAD) Study
| Vendor and Reader | Without CAD | With CAD | p | ||
|---|---|---|---|---|---|
| Raw Fraction | Estimate | Raw Fraction | Estimate | ||
| iCAD | |||||
| 1 | 60/149 | 0.40 (0.32–0.49) | 62/149 | 0.42 (0.34–0.50) | 0.500 |
| 2 | 82/150 | 0.55 (0.46–0.63) | 85/150 | 0.57 (0.48–0.65) | 0.250 |
| 3 | 76/149 | 0.51 (0.43–0.59) | 78/149 | 0.52 (0.44–0.61) | 0.500 |
| 4 | 65/150 | 0.43 (0.35–0.52) | 74/150 | 0.49 (0.41–0.58) | 0.004 |
| 5 | 100/150 | 0.67 (0.59–0.74) | 108/150 | 0.72 (0.64–0.79) | 0.008 |
| 6 | 61/149 | 0.41 (0.33–0.49) | 62/149 | 0.42 (0.34–0.50) | 1.000 |
| 7 | 34/149 | 0.23 (0.16–0.30) | 35/149 | 0.23 (0.17–0.31) | 1.000 |
| 8 | 95/150 | 0.63 (0.55–0.71) | 98/150 | 0.65 (0.57–0.73) | 0.250 |
| 9 | 66/150 | 0.44 (0.36–0.52) | 74/150 | 0.49 (0.41–0.58) | 0.008 |
| 10 | 58/150 | 0.39 (0.31–0.47) | 58/150 | 0.39 (0.31–0.47) | 1.000 |
| 11 | 71/150 | 0.47 (0.39–0.56) | 74/150 | 0.49 (0.41–0.58) | 0.250 |
| 12 | 72/150 | 0.48 (0.40–0.56) | 80/150 | 0.53 (0.45–0.62) | 0.008 |
| 13 | 58/150 | 0.39 (0.31–0.47) | 59/150 | 0.39 (0.31–0.48) | 1.000 |
| 14 | 119/150 | 0.79 (0.72–0.86) | 123/150 | 0.82 (0.75–0.88) | 0.219 |
| Average | 0.49 (0.40-0.57) | 0.51 (0.43-0.60) | 0.089 | ||
| R2 | |||||
| 1 | 62/150 | 0.41 (0.33–0.50) | 68/150 | 0.45 (0.37–0.54) | 0.031 |
| 2 | 52/150 | 0.35 (0.27–0.43) | 53/150 | 0.35 (0.28–0.44) | 1.000 |
| 3 | 87/150 | 0.58 (0.50–0.66) | 88/150 | 0.59 (0.50–0.67) | 1.000 |
| 4 | 75/149 | 0.50 (0.42–0.59) | 77/149 | 0.52 (0.43–0.60) | 0.500 |
| 5 | 73/150 | 0.49 (0.40–0.57) | 79/150 | 0.53 (0.44–0.61) | 0.031 |
| 6 | 86/150 | 0.57 (0.49–0.65) | 90/150 | 0.60 (0.52–0.68) | 0.125 |
| 7 | 100/150 | 0.67 (0.59–0.74) | 101/150 | 0.67 (0.59–0.75) | 1.000 |
| 8 | 88/150 | 0.59 (0.50–0.67) | 90/150 | 0.60 (0.52–0.68) | 0.625 |
| 9 | 88/150 | 0.59 (0.50–0.67) | 92/150 | 0.61 (0.53–0.69) | 0.125 |
| 10 | 82/150 | 0.55 (0.46–0.63) | 90/150 | 0.60 (0.52–0.68) | 0.021 |
| 11 | 75/150 | 0.50 (0.42–0.58) | 81/150 | 0.54 (0.46–0.62) | 0.031 |
| 12 | 80/150 | 0.53 (0.45–0.62) | 84/150 | 0.56 (0.48–0.64) | 0.125 |
| 13 | 73/150 | 0.49 (0.40–0.57) | 72/150 | 0.48 (0.40–0.56) | 1.000 |
| 14 | 48/150 | 0.32 (0.25–0.40) | 48/150 | 0.32 (0.25–0.40) | 1.000 |
| 15 | 79/150 | 0.53 (0.44–0.61) | 79/150 | 0.53 (0.44–0.61) | 1.000 |
| Average | 0.51 (0.46–0.56) | 0.53 (0.48–0.58) | 0.183 | ||
Note—Except where otherwise indicated, data shown are sensitivities with 95% CIs in parentheses. iCAD = SecondLook CAD system (version 1.4, iCAD), R2 = ImageChecker Cenova CAD system (version 1.0, Hologic).