TABLE 4.
Specificities for Computer-Aided Detection (CAD) Study
| Vendor and Reader | Without CAD | With CAD | p | ||
|---|---|---|---|---|---|
| Raw Fraction | Estimate | Raw Fraction | Estimate | ||
| iCAD | |||||
| 1 | 141/148 | 0.95 (0.90–0.98) | 140/148 | 0.95 (0.90–0.98) | 1.000 |
| 2 | 137/149 | 0.92 (0.86–0.96) | 137/149 | 0.92 (0.86–0.96) | 1.000 |
| 3 | 135/150 | 0.90 (0.84–0.94) | 132/150 | 0.88 (0.82–0.93) | 0.250 |
| 4 | 139/150 | 0.93 (0.87–0.96) | 134/150 | 0.89 (0.83–0.94) | 0.063 |
| 5 | 114/150 | 0.76 (0.68–0.83) | 112/150 | 0.75 (0.67–0.81) | 0.625 |
| 6 | 126/150 | 0.84 (0.77–0.89) | 126/150 | 0.84 (0.77–0.89) | 1.000 |
| 7 | 137/150 | 0.91 (0.86–0.95) | 137/149 | 0.92 (0.86–0.96) | 1.000 |
| 8 | 118/150 | 0.79 (0.71–0.85) | 115/150 | 0.77 (0.69–0.83) | 0.250 |
| 9 | 142/150 | 0.95 (0.90–0.98) | 139/150 | 0.93 (0.87–0.96) | 0.250 |
| 10 | 131/150 | 0.87 (0.81–0.92) | 128/150 | 0.85 (0.79–0.91) | 0.250 |
| 11 | 129/150 | 0.86 (0.79–0.91) | 129/150 | 0.86 (0.79–0.91) | 1.000 |
| 12 | 130/150 | 0.87 (0.80–0.92) | 127/150 | 0.85 (0.78–0.90) | 0.250 |
| 13 | 147/150 | 0.98 (0.94–1.00) | 147/150 | 0.98 (0.94–1.00) | 1.000 |
| 14 | 88/150 | 0.59 (0.50–0.67) | 78/149 | 0.52 (0.44–0.61) | 0.049 |
| Average | 0.89 (0.83–0.93) | 0.87 (0.81–0.92) | 0.146 | ||
| R2 | |||||
| 1 | 140/150 | 0.93 (0.88–0.97) | 140/150 | 0.93 (0.88–0.97) | 1.000 |
| 2 | 140/150 | 0.93 (0.88–0.97) | 139/150 | 0.93 (0.87–0.96) | 1.000 |
| 3 | 109/149 | 0.73 (0.65–0.80) | 107/148 | 0.72 (0.64–0.79) | 1.000 |
| 4 | 120/150 | 0.80 (0.73–0.86) | 115/150 | 0.77 (0.69–0.83) | 0.063 |
| 5 | 131/150 | 0.87 (0.81–0.92) | 130/150 | 0.87 (0.80–0.92) | 1.000 |
| 6 | 138/150 | 0.92 (0.86–0.96) | 135/150 | 0.90 (0.84–0.94) | 0.250 |
| 7 | 111/149 | 0.74 (0.67–0.81) | 108/149 | 0.72 (0.65–0.79) | 0.250 |
| 8 | 125/150 | 0.83 (0.76–0.89) | 122/150 | 0.81 (0.74–0.87) | 0.250 |
| 9 | 135/150 | 0.90 (0.84–0.94) | 136/150 | 0.91 (0.85–0.95) | 1.000 |
| 10 | 125/150 | 0.83 (0.76–0.89) | 115/150 | 0.77 (0.69–0.83) | 0.006 |
| 11 | 130/150 | 0.87 (0.80–0.92) | 130/150 | 0.87 (0.80–0.92) | 1.000 |
| 12 | 136/150 | 0.91 (0.85–0.95) | 136/150 | 0.91 (0.85–0.95) | 1.000 |
| 13 | 132/150 | 0.88 (0.82–0.93) | 133/150 | 0.89 (0.82–0.93) | 1.000 |
| 14 | 143/149 | 0.96 (0.91–0.99) | 143/149 | 0.96 (0.91–0.99) | 1.000 |
| 15 | 122/149 | 0.82 (0.75–0.88) | 120/149 | 0.81 (0.73–0.87) | 0.500 |
| Average | 0.87 (0.83–0.91) | 0.86 (0.82–0.90) | 0.238 | ||
Note—Except where otherwise indicated, data shown are specificities with 95% CIs in parentheses. iCAD = SecondLook CAD system (version 1.4, iCAD), R2 = ImageChecker Cenova CAD system (version 1.0, Hologic).