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. Author manuscript; available in PMC: 2016 Jan 21.
Published in final edited form as: J Biomech. 2014 Nov 28;48(2):310–317. doi: 10.1016/j.jbiomech.2014.11.028

Figure 6.

Figure 6

a. Bone volume, BV, versus days PF, with 95% CIs labeled. No changes were found in BV over the duration of the experiment in any of the groups (p=0.85). BV of intact and callus Pten-CKO femurs were nearly twice their respective WT counterparts at 28 days PF (p<0.01); and, BV of callus femurs of both Pten-CKO and WT were roughly twice their respective contralateral intact femurs (p<0.01).

b. Tissue mineral density, TMD, versus days PF, with 95% CIs labeled. TMD of intact femurs of both Pten-CKO and WT was found to significantly increase with time (slope 0.06, 95%: 0.01, 0.10, p=0.019). TMD of callus femurs of both Pten-CKO and WT significantly increased with time with a slope 0.04 units larger than intact femurs (95% CI: 0.02, 0.07, p=0.005). TMD of callus Pten-CKO femurs was significantly less than contralateral intact femurs at 14 and 21 days PF (p=0.009, p=0.010, respectively). TMD of callus WT femurs of the was significantly less than their respective contralateral intact femurs for all days PF (p=0.002, p=0.010, p=0.002, respectively).