Table 1.
Characteristics of mothers treated and not treated with granulocyte colony–stimulating factor and their neonates
| Diagnosis | All Participants and Pregnancies |
Participants and Pregnancies without G-CSF treatment |
Participants and Pregnancies with G-CSF treatment |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| # Patients (Pts) |
# Pregnancies (Preg) |
# Pts |
# Preg |
Mothers’ Age at delivery mean (SD) |
Neonates’ GA at delivery mean (SD) |
# Pts |
# Preg |
Mothers’ Age at delivery mean (SD) |
Neonates’ GA at delivery mean (SD) |
G-CSF Dose mcg/kg/day Median (Range) |
|
| Autoimmune | 4 | 8 | 2 | 2 | 33 (0.48) (n=2) | 40 (0.71) (n=2) | 4 | 6 | 33 (5.54) (n=6) | 38 (1.83) (n=4) | 0.11 (0.23 – 4.6) |
| Congenital | 15 | 21 | 3 | 4 | 26 (4.32) (n=4) | 41 (1.29) (n=4) | 12 | 17 | 29 (5.91) (n=7) | 39 (2.89) (n=15) | 2.13 (0.5 – 7.9) |
| Cyclic | 29 | 74 | 15 | 35 | 25* (4.13) (n=35) | 37 (7.64) (n=30) | 20 | 39 | 28* (4.82) (n=39) | 36 (10.1) (n=33) | 1.1 (0.07 – 8.6) |
| Idiopathic | 59 | 121 | 37 | 83 | 28 (6.19) (n=83) | 40* (1.69) (n=60) | 25 | 38 | 29 (4.89) (n=8) | 37* (7.71) (n=30) | 0.8 (0.02 – 5.7) |
| Total | 107 | 224 | 57 | 124 | 27* (5.76) (n=124) | 39* (4.65) (n=96) | 61 | 100 | 29* (5.12) (n=100) | 37* (8.0) (n=82) | 1.0 (0.02 – 8.6) |
*
Denotes significant difference (P<0.05) between untreated and treated patients for the diagnostic category, unpaired Student’s t-test