Table 1.
Baseline Characteristics of Randomized Patients (n[%]) for Which Follow-Up Colonoscopy and Toxicity Information is Available (N = 194)
| Baseline Characteristic | Calcium Carbonate (n = 95) |
Placebo (n = 99) |
|---|---|---|
| Sex | ||
| Male | 57 (60) | 65 (66) |
| Female | 38 (40) | 34 (34) |
| Stratification Factors | ||
| Site of Primary CRC | ||
| Colon | 76 (80) | 80 (81) |
| Rectum | 19 (20) | 19 (19) |
| Stage of Primary CRC | ||
| 0 | 7 (7) | 4 (4) |
| I | 51 (54) | 49 (50) |
| II | 37 (39) | 46 (46) |
| Adenomas Present | ||
| Yes | 60 (63) | 59 (60) |
| No | 35 (37) | 40 (40) |
| Descriptive Factors | ||
| Synchronous Adenomas | ||
| ≥ 4 | 12 (13) | 16 (16) |
| 0–3 | 83 (87) | 83 (84) |
| Primary CRC confined to polyp | ||
| Yes | 23 (24) | 23 (23) |
| No | 72 (76) | 76 (77) |
| Time of resection of primary CRC before randomization | ||
| < 6 months | 63 (66) | 64 (65) |
| 6–18 months | 32 (34) | 35 (35) |