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. Author manuscript; available in PMC: 2015 Jan 7.
Published in final edited form as: Radiat Res. 2012 Oct 23;178(5):499–503. doi: 10.1667/RR3042.2

FIG. 2.

FIG. 2

Panel A: Direct comparison of the effects of menadione and ionizing radiation and effects of combination treatment. Embryos received the indicated dose of 137Cs γ radiation, menadione or both at the pre-early gastrula stage (6 h after fertilization), and were processed for TUNEL staining at 24 h after fertilization. Orientation of embryos is the same as in Fig. 1. Panel B: Microinjection of Ku80 antisense MO affects sensitivity to radiation but not to menadione. Embryos were injected at the single-cell stage with ~5 ng of Ku80 MO (sub-panels d, e and f) or with the same volume of buffer only (sub-panels a, b and c). Arrows denote increase apoptosis in Ku80 MO-injected, irradiated embryo.