Sir John Gurdon with the author and some of his F2 from the De Robertis lab. The occasion was a symposium at EMBL to celebrate my 60th birthday in 2007. This is only part of the scientific progeny through just a single one of John Gurdon’s many trainees, and serves to illustrate the enormous influence Sir John has had on developmental biology. The lineage of most workers in the Xenopus development field can be traced back to him. From left to right: Thomas Bürglin, Edgar Pera, Abraham Fainsod, Christof Niehrs, Zétó Belo, Luc Leyns, Iain Mattaj, Sandra Piccolo, Ana De Robertis, Stefano Piccolo, Ghislaine Agius, Yoshiki Sasai, Eddy De Robertis, Rolf Zeller, Sir John Gurdon, Chris Wright, Hiroki Kuroda, Eric Agius, Martin Blum, Herbert Steinbeisser, Michael Oelgeschläger and Juan Larraín.