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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Nat Neurosci. 2014 Aug 17;17(9):1263–1269. doi: 10.1038/nn.3788

Fig. 5. Inter-problem multivoxel pattern stability in the hippocampus in children at Time-1 (T1) and Time-2 (T2), adolescents, and adults.

Fig. 5

(a) Event-related fMRI design of arithmetic problem solving task. (b) Sagittal slice of predefined region of interest (ROI) in the hippocampus used for the inter-problem pattern stability analysis. (c) 26 × 26 correlation matrix representing trial-by-trial brain activation pattern stability in the hippocampus during addition problem solving. (d-e) Inter-problem pattern stability in the left and right hippocampus for problems correctly solved by children at T1 and T2, adolescents, and adults. (f-g) Results of whole-brain analysis showing hippocampal regions that showed significant increases in inter-problem multivoxel pattern stability from childhood through adolescence into adulthood. Note that only correctly performed trials (problems) from each participant's event-related fMRI data were used in the analysis. Notes: a.u., arbitrary units; * P<0.05; **, P<0.01; L, left; R, right.