Skip to main content
. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Curr Opin Cardiol. 2014 May;29(3):207–213. doi: 10.1097/HCO.0000000000000050

Table 1.

Recently published reports of miRs that function in cardiomyocyte regeneration

Ref miR Function in cardiomyocyte (CM) regeneration Target genes in heart
34 miR-590 promote 7-day and 2 month postnatal CMs to re-enter cell cycle and progress through mitosis Homer1,Hopx and Clic5
34 miR-1825 increase the proliferation of 7-day postnatal CMs unclear
34 miR-33b increase the proliferation of 7-day postnatal CMs unclear
34, 52 miR-199a promote 7-day and 2 month CMs to re-enter cell cycle and progress through mitosis; facilitate a cardiac metabolic shift from fatty acid toward glucose metabolism Homer1, Hopx and PPARδ
52 miR-214 facilitate a cardiac metabolic shift from fatty acid toward glucose metabolism PPARδ
53, 57 miR-17-92 induce proliferation of CMs PTEN, Isl1 and Tbx1
60 miR-34a induce cell death and hypertrophy of CMs Pnuts
67, 69, 70, miR-15 family repress proliferation of CMs Chek1