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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Clin Cancer Res. 2014 Oct 21;21(1):193–200. doi: 10.1158/1078-0432.CCR-14-0748

Table 1.

Characteristics of the participants in the prospective cohort by gender and serum total bilirubin levels a

Characteristics Men (N = 202,902), N (%)
Women (N = 222,758), N (%)
Total Total bilirubin level (mg/dL)
Total Total bilirubin level (mg/dL)
>1 0.75–1 <0.75 >0.82 0.61–0.82 <0.61




Total 202,902 67,841 (33.4) 65,540 (32.3) 69,521 (34.3) 222,758 75,189 (33.8) 72,207 (32.4) 75,362 (33.8)
Age (y), mean (SD) 41 (14) 40 (14) 42 (14) 41 (14) 41 (14) 41 (14) 42 (14) 41 (13)
 20–39 112,584 (55.5) 39,399 (35.0) 35,270 (31.3) 37,915 (33.7) 119,946 (53.9) 41,854 (34.9) 37,510 (31.3) 40,582 (33.8)
 40–59 63,447 (31.3) 19,927 (31.4) 21,201 (33.4) 22,319 (35.2) 76,087 (34.2) 23,908 (31.4) 25,500 (33.5) 26,679 (35.1)
 ≥60 26,871 (13.2) 8,515 (31.7) 9,069 (33.8) 9,287 (34.6) 26,725 (12) 9,427 (35.3) 9,197 (34.4) 8,101 (30.3)
BMI (kg/m2), mean (SD) 23.9 (3.4) 23.5 (3.3) 23.9 (3.3) 24.2 (3.4) 22.3 (3.6) 21.8 (3.5) 22.3 (3.6) 22.8 (3.7)
 <25 134,591 (66.4) 47,499 (35.3) 43,264 (32.1) 43,828 (32.6) 176,567 (79.3) 62,056 (35.2) 57,139 (32.4) 57,372 (32.5)
 25–29.9 59,734 (29.5) 18,062 (30.2) 19,565 (32.8) 22,107 (37.0) 38,454 (17.3) 11,040 (28.7) 12,660 (32.9) 14,754 (38.4)
 ≥30 8,516 (4.2) 2,264 (26.6) 2,696 (31.7) 3,556 (41.8) 7,689 (3.5) 2,080 (27.1) 2,394 (31.1) 3,215 (41.8)
Educational levels
 Middle school or lower 40,499 (20.6) 12,823 (31.7) 13,379 (33.0) 14,297 (35.3) 70,385 (32.6) 23,109 (32.8) 23,546 (33.5) 23,730 (33.7)
 High school 45,601 (23.2) 14,665 (32.2) 14,693 (32.2) 16,243 (35.6) 54,124 (25.1) 17,238 (31.9) 17,186 (31.8) 19,700 (36.4)
 Junior college 45,367 (23.1) 15,705 (34.6) 14,526 (32.0) 15,136 (33.4) 42,941 (19.9) 15,153 (35.3) 13,525 (31.5) 14,263 (33.2)
 College or higher 64,987 (33.1) 22,603 (34.8) 20,844 (32.1) 21,540 (33.2) 48,400 (22.4) 17,428 (36.0) 15,692 (32.4) 15,280 (31.6)
Smoking status
 Non-smoker 92,864 (47.9) 35,175 (37.9) 30,188 (32.5) 27,501 (29.6) 188,685 (91.7) 64,488 (34.2) 61,534 (32.6) 62,663 (33.2)
 Smoker 101,092 (52.1) 29,632 (29.3) 32,451 (32.1) 39,009 (38.6) 17,123 (8.3) 4,891 (28.6) 5,228 (30.5) 7,004 (40.9)
  <30 pack-years 72,153 (74.9) 21,843 (30.3) 23,084 (32.0) 27,226 (37.7) 14,662 (91.7) 4,303 (29.4) 4,403 (30.0) 5,956 (40.6)
  ≥30 pack-years 24,146 (25.1) 6,269 (26.0) 7,777 (32.2) 10,100 (41.8) 1,327 (8.3) 279 (21) 434 (32.7) 614 (46.3)
Lung cancer incidence 809 (0.4) 215 (26.6) 270 (33.4) 324 (40.1) 524 (0.2) 155 (29.6) 187 (35.7) 182 (34.7)
Lung cancer mortality 614 (0.3) 147 (23.9) 214 (34.9) 253 (41.2) 330 (0.2) 107 (32.4) 115 (34.9) 108 (32.7)
a

Percentage may not total 100 because of rounding.