Fig. 6.
A comparison between the antiparallel actin dimer 1LCU (Bubb et al., 2002) and two states of the actin filament. A) When chain A of the dimer (in yellow) is superimposed upon one subunit (red) in our model for canonical F-actin (1.1 A rmsd, over 236 Cα pairs), the second chain of the dimer (in green) makes extensive clashes with another protomer in the filament (arrow). B) When the same chain A of 1LCU (in yellow) is superimposed upon a protomer in the T1 actin (in red) (1.3 A rmsd, over 242 Cα pairs), the second chain of the dimer (in green) makes no significant clashes with the filament.