Table 2.
Multivariable Linear Regression Models Predicting OT (log; pg/ml) Stratified by T1DM
| Control (n=74) | T1DM (n=88) | |||
|---|---|---|---|---|
| Variables | β | p value | β | p value |
| Health Behaviors | ||||
| Quartiles of alcohol intakea | - | −0.08 | 0.007 | |
| Quartiles of caffeine intakeb | - | 0.09 | 0.005 | |
| Taking calcium supplementc | - | 0.14 | 0.04 | |
| Reproductive History | ||||
| Estrogen contraceptive used | 0.22 | 0.0004 | - | |
| Quartiles of lifetime contraceptive estrogen exposuree | - | −0.09 | 0.003 | |
| Adiposity | ||||
| Change in weightf | −0.14 | 0.046 | - | |
| Waist-to-hip ratio (1/10th unit) | - | −0.21 | 0.18 | |
| Leptin (pg/ml) | - | 0.01 | 0.02 | |
| Bone | ||||
| RANKL (log; pg/ml) | 0.18 | 0.02 | - | |
| Diabetes Specific Factors | ||||
| Insulin dose (1/10th unit/kg) | - | −0.34 | 0.02 | |
| Interaction | ||||
| Insulin dose * waist-to-hip ratio | - | 0.04 | 0.02 | |
| Adjusted R2 | 0.18 | 0.39 | ||
Note. RANKL, Receptor Activator of Nuclear factor κβ Ligand
a
0=0–1.08 grams/day, 1=1.09–3.11 grams/day, 2=3.12–8.64 grams/day, 3=8.65–79.18 grams/day
b
0=0–33.6 mgs/day, 1=33.7–94.4 mgs/day, 2=94.5–171.3 mgs/day, 3=171.4–709.1 mgs/day
c
0=no, 1=yes
d
0=never, 1=former, 2=current
e
0=0–0.93 mgs, 1=0.94–17.19 mgs, 2=17.20–47.78 mgs, 3=47.79–192.47 mgs
f
0=lost ≥ 10 pounds, 1=maintained (± 9.9 pounds), 2=gained ≥ 10 pounds