Table 4.
Baseline and Longitudinal Prodromal HD Group Differences Relative to Controls for Participant and Companion ECog
Baseline Group Difference | ||||||
---|---|---|---|---|---|---|
Variable | Low | Medium | High | |||
Estimate (SE) | t- value |
Estimate (SE) | t-value | Estimate (SE) | t-value | |
P Total | 0.015 (0.039) | 0.37 | 0.086 (0.034) | 2.48c | 0.15 (0.032) | 4.66a |
P Memory | 0.016 (0.052) | 0.31 | 0.11 (0.046) | 2.47c | 0.15 (0.042) | 3.59a |
P Language | 0.07 (0.042) | 1.68 | 0.16 (0.037) | 4.27a | 0.23 (0.034) | 6.62a |
P Vsp. perception | 0.016 (0.036) | 0.44 | 0.029 (0.032) | 0.91 | 0.097 (0.029) | 3.34a |
P Exe. function | −0.014 (0.044) | −0.31 | 0.087 (0.039) | 2.24c | 0.15 (0.036) | 4.19a |
C Total | −0.022 (0.035) | −0.62 | 0.062 (0.031) | 2.02c | 0.17 (0.029) | 5.86a |
C Memory | −0.038 (0.047) | −0.82 | 0.089 (0.041) | 2.15c | 0.17 (0.039) | 4.47a |
C Language | 0.015 (0.033) | 0.46 | 0.10 (0.029) | 3.53a | 0.20 (0.027) | 7.35a |
C Vsp. perception | −0.025 (0.032) | −0.80 | 0.0042 (0.028) | 0.15 | 0.11 (0.026) | 4.23a |
C Exe. function | −0.025 (0.046) | −0.53 | 0.069 (0.041) | 1.67 | 0.21 (0.038) | 5.57a |
Longitudinal Group Difference | ||||||
Stub head | Low | Medium | High | |||
Estimate (SE) |
t value |
Estimate (SE) | t-value | Estimate (SE) | t-value | |
P Total | 0.012 (0.015) | 0.82 | 0.036 (0.013) | 2.71b | 0.028 (0.012) | 2.30c |
P Vsp. Perception | 0.011 (0.015) | 0.76 | 0.033 (0.013) | 2.55c | 0.026 (0.012) | 2.27c |
C Total | 0.026 (0.021) | 1.23 | 0.047 (0.019) | 2.39c | 0.052 (0.018) | 2.94b |
C Memory | 0.032 (0.027) | 1.20 | 0.054 (0.024) | 2.24c | 0.052 (0.022) | 2.39c |
C Exe. Function | 0.032 (0.029) | 1.11 | 0.062 (0.026) | 2.38c | 0.069 (0.024) | 2.91b |
Note. P = participant C = companion Vsp. = visuospatial Exe. = executive.
p<0.001,
p<0.01,
p<0.05,