Table 3.

Mutation spectrum for α-gene and its coinheritance with other mutations

Categories	No. of samples analysed	Single deletions		Double deletions			Triplications		Total
		α3.7/αα	α4.2/αα	α3.7/α3.7	α4.2/α4.2	α3.7/α4.2	αααanti3.7	αααanti4.2
Suspected samples	480	53	24	14	6	23	13	3	136
HbS/E variants	56	7	5	2	2	1	0	0	17
β-gene mutants	56	3	1	0	0	2	0	0	6
Controls	347	27	07	01	03	01	06	01	46
Total	939	90	37	17	11	27	19	4	205

α^3.7/αα and α^4.2/αα represent single gene deletion; α^3.7/α^3.7, α^4.2/α^4.2 and α^3.7/α^4.2 represent double gene deletions; and ααα^anti3.7 and ααα^anti4.2 represent α-gene triplications