Table 1.
Effects of naftopidil and its derivatives on the cell cycle progression of HT29 cells
Phase (%) | |||
---|---|---|---|
G0/G1 | S | G2/M | |
Control | 63.6 ± 1.0 | 24.8 ± 0.1 | 10.6 ± 0.7 |
Naftopidil | 77.0 ± 1.1*** | 15.0 ± 1.1** | 7.1 ± 0.2* |
TG09-01 | 68.7 ± 1.2** | 18.9 ± 0.8** | 10.2 ± 0.6 |
TG09-02 | 71.7 ± 1.6** | 18.6 ± 1.5* | 8.9 ± 0.3* |
*p < 0.05; **p < 0.01; ***p < 0.001 versus vehicle-treated control