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. Author manuscript; available in PMC: 2015 Jan 8.
Published in final edited form as: J Nutr Biochem. 2007 Mar 23;18(9):597–608. doi: 10.1016/j.jnutbio.2006.11.005

Table 1.

Effects of dietary copper and iron deprivation on hematocrit, plasma ceruloplasmin, liver copper and ferritin iron. Data are Means ± SD for the N in parentheses.

Nutritional Copper or Iron Status
Parameter Deficient Supplemented Excess
A. Rats on low copper diets
Hematocrit (%) 40 ± 6 (5) 45 ± 6 (5) --
Plasma ceruloplasmin (p-phenylene diamine oxidase activity) (nmol/min/mL) 0.072 ± 0.008 (3)* 0.125 ± 0.010 (3) --
Liver copper (μg/g) 2.1 ± 0.4 (4)* 3.5 ± 0.9 (5) --
B. Rats on low iron diets
Hematocrit (%) 14 ± 5 (6)* 45 ± 6 (8) 45 ± 5 (5)
Liver ferritin Fe (μg/g) 4 ± 4 (6)* 31 ± 7 (8) 100 ± 37 (5)*
Liver copper (μg/g) 11 ± 5 (4)° 6 ± 2 (4) 4 ± 1 (4)
*

p < 0.025- <0.001 for difference from supplemented rats by Student’s t-test

°

p < 0.05 for difference from excess Fe treated rats