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. 2015 Jan 6;108(1):194–202. doi: 10.1016/j.bpj.2014.10.070

Figure 3.

Figure 3

Mutation dynamics trajectories for four viral ssRNA sequences. (Top to bottom) BMV RNA2 and RNA1 segments from the tripartite genome of BMV (Bromoviridae), OnYMV (Tymoviridae), and ERBV1 (Picornaviridae). Each panel shows nine 〈MLD〉 trajectories and their average value (blue) for each sequence in units of MC steps, N/100. (Red dot-dashed lines and green dashed lines) 〈MLD〉 values of WT RNAs and the MLD¯ values of random RNAs (for viral-like composition, Eq. 3), respectively. Note that in the case of OnYMV, a Tymovirus, we must consider the appropriate asymptotic value of MLD¯ for random RNAs with Tymoviridae-like composition (see Fig. 1). This value is shown in the figure (orange short-dashed line). (To see this figure in color, go online.)