Table 1.

Clinical characteristics and telomerase activity status of pediatric ependymoma cohort

Clinical characteristics	Patients		5-year PFS			5-year OS
	#	%	%	SE	Log-rank (p)	%	SE	Log-rank (p)
Age >3 years
Yes	25	69	51	12	0.36	46	15	0.36
No	11	31	18	16		36	21
Sex
Male	26	72	44	13	0.30	45	16	0.20
Female	10	28	35	16		42	17
Tumor location
Supratentorial	13	36	32	16	0.16	45	21	0.97
Infratentorial	23	64	46	13		42	16
Grade
2	14	39	42	17	0.45	69	19	0.02*
3	22	61	41	12		25	14
Resection
GTR	21	58	49	14	0.35	54	17	0.07
Subtotal	13	36	31	15		33	18
Biopsy	2	6	50	35		50	35
Radiation
Yes	25	69	51	12	0.03*	53	16	0.03*
No	11	31	20	16		21	17
Chemotherapy
Yes	21	58	40	14	0.94	45	16	0.75
No	15	42	43	15		41	20
Telomerase activity
Yes	23	64	29	11	0.03*	58	12	0.05*
No	13	36	64	18		83	15

PFS Progression-free survival, OS overall survival, SE standard error, GTR gross total resection

* Significance as determined by log-rank statistics at p ≤ 0.05